Presentation

- Single-cell analysis of ~200,000 cells in HCC and fetal liver leads to the discovery of a shared onco-fetal ecosystem that drives immunosuppressive macrophages (Sharma et. al., 2020)

- Ever wondered why chemotherapy works for some patients but not for others? Well, we did, and discovered that tumors evolve differently under the selection pressure of same drug and ‘fate’ lies in the ‘fidelity of stem-cell hierarchy’.